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Why Does Cannabis Affect People Differently?

Have you noticed that cannabis may produce different effects for you compared to your friends or family? Whether you’re consuming products containing high amounts of CBD, THC, or any of the other numerous cannabinoids found in all forms of cannabis there’s probably been some disparity from person to person in terms of effectiveness. You may have read success stories online or heard from a friend that taking CBD has helped them overcome their anxiety, drastically reduced pain, or perhaps they felt little to no change, well, there are scientific reasons behind the wide-spread claims. Going back to 1964, shortly after Raphael Mechoulam, an Israeli chemist, discovered psychoactive THC he decided to test out its effects on his friends. He dosed...

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Introduction to The Endocannabinoid System

It is obvious that the consumption of cannabis has a profound effect on the body, but what makes these psychoactive and physiological changes take place? This is due to the endocannabinoid system, located throughout the body in the brain, organs, connective tissues, glands, immune cells and is composed of three key components – cannabinoid receptors, endocannabinoids and metabolic enzymes. No matter where in the body the goal for the endocannabinoid system is always the same: homeostasis, which is the maintenance of a stable internal environment despite fluctuations in the external environment. Leafly.com presented the perfect example by presenting the correlation between homeostasis and Goldilocks and The Three Bears. Conditions need to be just right for our cells to maintain optimum...

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Is CBD from Hemp the Same as CBD from MMJ?

A common question amongst people interested in the benefits of CBD and those already versed in the MMJ community is whether CBD from hemp is as good as CBD from marijuana. It is a common misconception that hemp-derived CBD is considered “less potent” or not as effective but it should come as no surprise the similarities between hemp and marijuana since they are both versions of Cannabis Sativa. On a molecular level, CBD from hemp is exactly the same as CBD from marijuana. The body does not care where the CBD comes from since it cannot tell the difference. This is amazing considering all the people who have limited to no access to state-approved medical marijuana now have the ability...

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Isolate vs Full Spectrum

There is a constant debate in regards to the benefit of products containing CBD isolate vs. a full spectrum CBD product. First – we need to understand the difference between the two. When a product is labeled as full spectrum - whether it be a tincture, topical or edible - these products contain multiple cannabinoids such as CBD, CBG, CBN, CBC and THC with CBD being the most prominent with THC content falling under the legal limit. Products containing CBD isolate are products that contain only CBD and no other cannabinoids.  It has been stated that using full spectrum CBD products allows for what is referred to as the “entourage effect” which basically states that CBD is more effective while...

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CBD vs. THC

What makes CBD non-psychoactive as opposed to THC? Let’s take some time to clear up any misunderstandings you might have when it comes to CBD and psychoactivity. When addressing psychoactivity we first need to talk about the body’s endocannabinoid system. The endocannabinoid system is a group of endogenous cannabinoid receptors located in the mammalian brain and throughout the central and peripheral nervous systems (outside the brain and spinal cord), consisting of neuromodulatory lipids and their receptors. If I’ve lost you, not to worry, we’re only focusing on the CB1 receptors which are just a part of the endocannabinoid system. CB1 receptors are concentrated in the brain and central nervous system. The difference between CBD and THC boils down to the...

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