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Introduction to The Endocannabinoid System

It is obvious that the consumption of cannabis has a profound effect on the body, but what makes these psychoactive and physiological changes take place? This is due to the endocannabinoid system, located throughout the body in the brain, organs, connective tissues, glands, immune cells and is composed of three key components – cannabinoid receptors, endocannabinoids and metabolic enzymes. No matter where in the body the goal for the endocannabinoid system is always the same: homeostasis, which is the maintenance of a stable internal environment despite fluctuations in the external environment. Leafly.com presented the perfect example by presenting the correlation between homeostasis and Goldilocks and The Three Bears. Conditions need to be just right for our cells to maintain optimum...

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Dr. Sanjay Gupta on CBD

Dr. Sanjay Gupta, CNN’s Chief Medical Correspondent is a practicing neurosurgeon and until recent years was a booming voice in the campaigns against cannabis. It came as a huge surprise as Gupta recanted his prior arguments made against the benefits of using cannabis, especially after being behind pieces with titles as straightforward as “Why I Would Vote No on Pot” – published in Time Magazine in 2009. Regardless, Dr. Sanjay Gupta is a welcomed addition to the fight against the disinformation surrounding cannabis. In late 2013 Gupta presented the facts in the first of his two-part documentary about cannabis simply entitled Weed on CNN, the second of which later aired a few months later in March of 2014. In this...

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History of Hemp

In honor of Hemp History Week, we’re going to look back at the possible origins and earliest known uses and applications of hemp, leading us to learn how hemp made its way to the United States. It’s been said that hemp is possibly one of the earliest plants to have been cultivated. An archeological site in the Oki Islands near Japan contained cannabis achenes (a type of dry fruit produced by many species of flowering plants) from about 8000 BC, possibly signifying the use of the plant. Later in China, it has been known through historical documentation and archeology that hemp was used to make clothes, shoes, ropes and early forms of paper. Textile expert Elizabeth Wayland Barber summarizes the...

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Is CBD from Hemp the Same as CBD from MMJ?

A common question amongst people interested in the benefits of CBD and those already versed in the MMJ community is whether CBD from hemp is as good as CBD from marijuana. It is a common misconception that hemp-derived CBD is considered “less potent” or not as effective but it should come as no surprise the similarities between hemp and marijuana since they are both versions of Cannabis Sativa. On a molecular level, CBD from hemp is exactly the same as CBD from marijuana. The body does not care where the CBD comes from since it cannot tell the difference. This is amazing considering all the people who have limited to no access to state-approved medical marijuana now have the ability...

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How to Boost CBD's Bioavailability

There are many variations when it comes to CBD’s bioavailability once it’s been consumed. Only a certain percentage will produce active effects which relies strongly on the manner in which you consume CBD. There are two main reasons why this happens which relate to the way CBD metabolizes in your body. First, CBD isn’t water soluble thus CBD does not like to stay in the bloodstream. Instead, it diffuses outward and accumulates into your fatty tissues. This significantly reduces the amount of bioactive CBD that enters your systemic circulation, permitting less CBD to be carried to the active sites throughout your body. Second, when an organic compound like CBD enters your gut, it must pass through the liver before it...

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